Elevated aminotransferase levels: Diagnostic approach

Diagnostic value of elevated serum miRNA-143 levels in sepsis

OBJECTIVE To evaluate serum micro RNA-143 (miR-143) levels in patients with sepsis or non-infectious systemic inflammatory response syndrome (SIRS), and investigate its possible diagnostic or prognostic value. METHODS Serum was obtained from patients with sepsis or SIRS and healthy control subjects. Relative miR-143 expression was determined using quantitative real time polymerase chain react...

obesity measures and elevated levels of alanine aminotransferase: a population based study

background: obesity may lead to various morbidity including liver diseases. the present study was done to determine which obesity indices, including body mass index (bmi), waist circumference (wc), waist to hip ratio (whr), and waist to height ratio (whtr) have the stronger association with rising levels of alanine aminotransferase (alt). material and methods: of 6143 subjects aged ≥ 10 years o...

Clinical Relevance and Discriminatory Value of Elevated Liver Aminotransferase Levels for Dengue Severity

BACKGROUND Elevation of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) is prominent in acute dengue illness. The World Health Organization (WHO) 2009 dengue guidelines defined AST or ALT ≥ 1000 units/liter (U/L) as a criterion for severe dengue. We aimed to assess the clinical relevance and discriminatory value of AST or ALT for dengue hemorrhagic fever (DHF) and severe den...

Elevated Aspartate and Alanine Aminotransferase Levels and Natural Death among Patients with Methamphetamine Dependence

BACKGROUND Methamphetamine is one of the fastest growing illicit drugs worldwide, causing multiple organ damage and excessive natural deaths. The authors aimed to identify potential laboratory indices and clinical characteristics associated with natural death through a two-phase study. METHODS Methamphetamine-dependent patients (n = 1,254) admitted to a psychiatric center in Taiwan between 19...

Elevated irisin and alanine aminotransferase levels in hypothyroidism: role of oxidative stress?